Tactically this is what works for me:
The more fighter bays the better.
Two on the lead ship, two each on of the wing-men.
Bolter Drones seem to be the best.
Max Ships Upgrade from 2 to 5, then Hull Damage Upgrade, leave Shield Damage Upgrade alone unless you have green to burn.
A cloud of 30 drones makes very quick work of any opposing ships and is also an excellent incoming missile screen.
Next, a Nuke Cannon or two, help the Nuke rounds get to through with Missile Turrets.
Do not buy Speed Upgrades for the Nuke Cannon, the Missile Turret and Nuke Cannon rounds move at the same speed.
Buy Burst Upgrades for the Missile Turret.
With luck the opposing ship's anti-missile point defense targets the three missiles and a few more nukes get through.
Buy cheap bolters to shoot down a few incoming missiles, swap them out with salvaged bolters or gatlings as opportunity allows, save the green for the drones and nukes.
Keep your best bolter/gatling pointed at the incoming missiles.
Shield Boosts in are okay, but they are useless for incoming missiles.
Mid-range is comfortable. Long range is okay but just takes a while longer. Short range is okay, but opens your ships to too much punishment.
Jump out/run if you are getting torn up. You'll get chased but the very first thing the pursuers get is a face full of nukes when they jump in, quickly followed by what remains of the drone cloud.
